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Pharmaceuticals | Free Full-Text | In Vitro, In Vivo and In Silico  Characterization of a Novel Kappa-Opioid Receptor Antagonist
Pharmaceuticals | Free Full-Text | In Vitro, In Vivo and In Silico Characterization of a Novel Kappa-Opioid Receptor Antagonist

Frontiers | Crosstalk Between Kappa Opioid and Dopamine Systems in  Compulsive Behaviors
Frontiers | Crosstalk Between Kappa Opioid and Dopamine Systems in Compulsive Behaviors

Early life stress dysregulates kappa opioid receptor signaling within the  lateral habenula - ScienceDirect
Early life stress dysregulates kappa opioid receptor signaling within the lateral habenula - ScienceDirect

Dynorphin Controls the Gain of an Amygdalar Anxiety Circuit - ScienceDirect
Dynorphin Controls the Gain of an Amygdalar Anxiety Circuit - ScienceDirect

Pharmaceuticals | Free Full-Text | In Vitro, In Vivo and In Silico  Characterization of a Novel Kappa-Opioid Receptor Antagonist
Pharmaceuticals | Free Full-Text | In Vitro, In Vivo and In Silico Characterization of a Novel Kappa-Opioid Receptor Antagonist

Molecules | Free Full-Text | Solving an Old Puzzle: Elucidation and  Evaluation of the Binding Mode of Salvinorin A at the Kappa Opioid Receptor
Molecules | Free Full-Text | Solving an Old Puzzle: Elucidation and Evaluation of the Binding Mode of Salvinorin A at the Kappa Opioid Receptor

Development of κ Opioid Receptor Antagonists | Journal of Medicinal  Chemistry
Development of κ Opioid Receptor Antagonists | Journal of Medicinal Chemistry

Compartment-specific opioid receptor signaling is selectively modulated by  different dynorphin peptides | eLife
Compartment-specific opioid receptor signaling is selectively modulated by different dynorphin peptides | eLife

Pharmaceuticals | Free Full-Text | In Vitro, In Vivo and In Silico  Characterization of a Novel Kappa-Opioid Receptor Antagonist
Pharmaceuticals | Free Full-Text | In Vitro, In Vivo and In Silico Characterization of a Novel Kappa-Opioid Receptor Antagonist

Nalfurafine, a G-Protein–Biased KOR (Kappa Opioid Receptor) Agonist,  Enhances the Diuretic Response and Limits Electrolyte Losses to  Standard-of-Care Diuretics | Hypertension
Nalfurafine, a G-Protein–Biased KOR (Kappa Opioid Receptor) Agonist, Enhances the Diuretic Response and Limits Electrolyte Losses to Standard-of-Care Diuretics | Hypertension

Comparison of Pharmacological Properties between the Kappa Opioid Receptor  Agonist Nalfurafine and 42B, Its 3-Dehydroxy Analogue: Disconnect between  in Vitro Agonist Bias and in Vivo Pharmacological Effects | ACS Chemical  Neuroscience
Comparison of Pharmacological Properties between the Kappa Opioid Receptor Agonist Nalfurafine and 42B, Its 3-Dehydroxy Analogue: Disconnect between in Vitro Agonist Bias and in Vivo Pharmacological Effects | ACS Chemical Neuroscience

Prefrontal Cortical Kappa-Opioid Receptor Modulation of Local  Neurotransmission and Conditioned Place Aversion | Neuropsychopharmacology
Prefrontal Cortical Kappa-Opioid Receptor Modulation of Local Neurotransmission and Conditioned Place Aversion | Neuropsychopharmacology

A systematic review on the kappa opioid receptor and its ligands: New  directions for the treatment of pain, anxiety, depression, and drug abuse -  ScienceDirect
A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse - ScienceDirect

κ-opioid receptor - Wikipedia
κ-opioid receptor - Wikipedia

Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that  Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine  | Journal of Pharmacology and Experimental Therapeutics
Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine | Journal of Pharmacology and Experimental Therapeutics

Development of κ opioid receptor antagonists. - Abstract - Europe PMC
Development of κ opioid receptor antagonists. - Abstract - Europe PMC

Chronic Kappa opioid receptor activation modulates NR2B: Implication in  treatment resistant depression | Scientific Reports
Chronic Kappa opioid receptor activation modulates NR2B: Implication in treatment resistant depression | Scientific Reports

Kappa opioid receptors in the central amygdala modulate spinal nociceptive  processing through an action on amygdala CRF neurons | Molecular Brain |  Full Text
Kappa opioid receptors in the central amygdala modulate spinal nociceptive processing through an action on amygdala CRF neurons | Molecular Brain | Full Text

Pharmaceuticals | Free Full-Text | In Vitro, In Vivo and In Silico  Characterization of a Novel Kappa-Opioid Receptor Antagonist
Pharmaceuticals | Free Full-Text | In Vitro, In Vivo and In Silico Characterization of a Novel Kappa-Opioid Receptor Antagonist

Peripheral kappa opioid receptor activation drives cold hypersensitivity in  mice | bioRxiv
Peripheral kappa opioid receptor activation drives cold hypersensitivity in mice | bioRxiv

Opioid Receptor-Mediated Regulation of Neurotransmission in the Brain. -  Abstract - Europe PMC
Opioid Receptor-Mediated Regulation of Neurotransmission in the Brain. - Abstract - Europe PMC

The Role of Dynorphin and the Kappa Opioid Receptor in the Symptomatology  of Schizophrenia: A Review of the Evidence
The Role of Dynorphin and the Kappa Opioid Receptor in the Symptomatology of Schizophrenia: A Review of the Evidence

Compartment-specific opioid receptor signaling is selectively modulated by  different dynorphin peptides | eLife
Compartment-specific opioid receptor signaling is selectively modulated by different dynorphin peptides | eLife

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist  Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical  Neuroscience
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical Neuroscience

A systematic review on the kappa opioid receptor and its ligands: New  directions for the treatment of pain, anxiety, depression, and drug abuse -  ScienceDirect
A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse - ScienceDirect

Nalfurafine, a G-Protein–Biased KOR (Kappa Opioid Receptor) Agonist,  Enhances the Diuretic Response and Limits Electrolyte Losses to  Standard-of-Care Diuretics | Hypertension
Nalfurafine, a G-Protein–Biased KOR (Kappa Opioid Receptor) Agonist, Enhances the Diuretic Response and Limits Electrolyte Losses to Standard-of-Care Diuretics | Hypertension